Non-ablative photonic devices and related methods

A method of delivering light energy to the pathological tissue of a mammal at the skin or other external tissue, the method comprising:

• emitting first light energy from a first optical element;
• producing a substantially uniform first irradiance profile from the first light energy;
• transmitting the first light energy along a first optical path from the first optical element through a distal end surface of a second optical element directly, and in a first axial direction, to a surface of the pathological tissue in a non-invasive manner without ablating the pathological tissue;
• emitting second light energy from a third optical element;
• producing a substantially uniform second irradiance profile from the second light energy;
• and
• transmitting the second light energy along a second optical path from the third optical element through a distal end surface of a fourth optical element directly, and in the first axial direction, to the surface of the pathological tissue in a non-invasive manner without ablating the pathological tissue;
• wherein the first light energy and the second light energy do not overlap one another at the surface of the pathological tissue and do overlap one another at a depth below the surface of the pathological tissue.