Localised transdermal iontophoretic drug delivery system

A localized transdermal iontophoretic drug delivery system, wherein the system comprises:

• (a) an electrode assembly array, wherein the electrode assembly array comprises N electrode assemblies, and N≥3;
• each electrode assembly comprises one or more electrodes, the number of electrodes is an even number, and the one or more electrodes comprise a contact layer for contacting the electrode with a skin layer of a face having an external surface;
• and
• (b) M power sources, wherein each power source corresponds to an electrode of the electrode assembly array or a pair of electrodes of the electrode assembly array, and each power source is used for supplying a current to the corresponding electrode of the electrode assembly array or the pair of the corresponding electrodes of the electrode assembly array, wherein M is a positive integer from 2 to C (N, 2), wherein C (N, 2) is defined as (N!)/(2!*(N−2)!);
• wherein, at least two electrodes in the electrode assembly array are provided with a medium containing an electrically charged active agent, and the current supplied by one of the M power sources pushes the active agent to the skin layer during a time period in which the current has the same polarity as the active agent;
• wherein the one or more electrodes in the electrode assembly array is connected to a half-bridge drive circuit (HBD) and is driven by the HBD, ≥50% of the electrodes of the N electrode assemblies are reconfigurable, and the corresponding electrode and power source pairing can be changed during operation;
• wherein the HBD further comprises:
• a current sensor arranged on the high voltage side;
• and/or a current sensor arranged on the low voltage side;
• wherein the current supplied to at least two of the electrodes in the electrode assembly array are independently controlled by the HBD or the M power sources,
• wherein the system is an electronic facial mask, wherein a contact surface formed by the contact layer of the electrodes in the electrode assembly array is conformable to the external surface of the face;
• and wherein the system configures the electrodes of the electrode assembly array and/or controls the operating state of the electrodes based on a collected data of the face.