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US 12,636,387 B2Granted
Systems and methods for creating custom brachytherapy carriers
AssigneeGt Medical Technologies, Inc.
InventorsHeidi Cole, David Brachman, John Baker, Adam Turner
Life of this patent
Estimating the term…
Abstract
Custom radioactive seed carriers are fabricated pre-operatively and/or intra-operatively to more precisely match carrier specification of a radiation treatment plan for a particular patient. One or more carrier specification component, such as a 3D printer, injection molding system, machining component, or bioprinter, may be utilized to create the custom carrier.
Claims20
A method comprising:
- receiving treatment specifications including at least a tumor cavity size and shape and a radiation dose;
- determining a carrier configuration based on the treatment specifications, the carrier configuration indicating, for at least a first custom carrier, a carrier shape and a radioactive seed quantity;
- based at least on the carrier configuration, generating the first custom carrier using one or more custom carrier components, the one or more custom carrier components including one or more of a 3D printer, injection molding system, machining component, or bioprinter;
- based at least on the radioactive seed quantity indicated in the carrier configuration, inserting one or more radioactive seeds into the first custom carrier according to a seed position indicated in the treatment specifications;
- and
- providing the first custom carrier for implantation into a cavity of a particular mammal.
3 more elements
A method comprising:
- receiving treatment specifications including at least a tumor cavity size and shape and a radiation dose;
- determining a carrier configuration based on the treatment specifications, the carrier configuration indicating, for at least a first custom carrier, a carrier shape and a radioactive seed quantity;
- based at least on the carrier configuration, determining a custom mold configuration;
- providing the custom mold configuration to a 3D printer;
- forming the first custom carrier using a custom mold created by the 3D printer;
- based at least on the radioactive seed quantity indicated in the carrier configuration, inserting one or more radioactive seeds into the first custom carrier;
- lyophilizing the first custom carrier;
- sterilizing the first custom carrier;
- and
- initiating transport of the first custom carrier to an implantation location, wherein the first custom carrier is specially designed for implantation into a cavity of a particular mammal.
7 more elements
A method comprising:
- receiving treatment specifications including at least a tumor cavity size and shape and a radiation dose;
- determining a desired carrier configuration based on the treatment specifications, the desired carrier configuration indicating, for at least a first custom carrier, a carrier shape and a radioactive seed quantity;
- determining a closest fit carrier already fabricated and available for implantation, the closest fit carrier having an available carrier configuration, and:
- in response to determining, based on a comparison of that the available carrier configuration with the desired carrier configuration, that the closest fit carrier is not satisfactory, generating the first custom carrier using one or more custom carrier components, the one or more custom carrier components including one or more of a 3D printer, injection molding system, machining component, or bioprinter;
- or
- in response to determining, based on a comparison of that the available carrier configuration with the desired carrier configuration, that the closest fit carrier is satisfactory, initiating retrieval of the closest fit carrier without generating the first custom carrier.
3 more elements
A method comprising:
- receiving treatment specifications including at least a tumor cavity size and shape and a radiation dose;
- determining a desired carrier configuration based on the treatment specifications, the desired carrier configuration indicating, for a custom carrier, a carrier shape and a radioactive seed quantity;
- determining whether a surgery where implantation of the custom carrier will be performed is less than a threshold time period away, and:
- in response to determining that the surgery is less than a threshold time period away, determining a closest fit carrier already fabricated and available for implantation, the closest fit carrier having an available carrier configuration closest to the desired carrier configuration, and initiating retrieval of the closest fit carrier;
- or
- in response to determining that the surgery is not less than a threshold time period away, initiating generation of the custom carrier having the desired carrier configuration using one or more custom carrier components, the one or more custom carrier components including one or more of a 3D printer, injection molding system, machining component, or bioprinter.
3 more elements
Dependencies are inferred from the claim text.