Indane-, indene-, azaindane-, and azaindene-amines as activators of serotonin receptors

A compound of Formula (Ib):

• wherein:
• R1 is hydrogen, deuterium, or C1-C6 alkyl;
• or
• R1 and R2 can be taken together to form a 3-7 membered ring;
• R2 is hydrogen, deuterium, C1-C6 alkyl, or C3-C6 cycloalkyl, wherein said C1-C6 alkyl is optionally substituted with C5-C6 aryl, wherein said aryl is optionally substituted with —OH;
• or
• R2 is taken together with R1 to form a 3-7 membered ring;
• R3, R4, and R5 are independently hydrogen, deuterium, halogen, —OR11, —CF3, C1-C6 alkyl, or C1-C6 heteroalkyl;
• R6 is hydrogen or deuterium;
• A is nitrogen or —C(H)—;
• B is nitrogen, —C(H)—, or —C(OR8)—;
• E is —C(H)—, —C(OH)—, —C(OR8)—;
• or
• A or E is optionally sulfur while B is omitted resulting in a 5 membered thiophene ring;
• C is carbon or nitrogen;
• R7 is hydrogen, deuterium, or C1-C6 alkyl;
• R8 is C1-C6 alkyl;
• X is hydrogen, deuterium, halogen, —OH, —OR11, —SO2NHR11, —SO2N(R11)2, —SO2R11, —NH2, —NR11, —CN, —COOR11, —COR11, —CONR11, —NCOR11, C1-C6 alkyl, or C1-C6 heteroalkyl, wherein said C1-C6 alkyl, or C1-C6 heteroalkyl is optionally substituted with C3-C6 cycloalkyl, or X is absent;
• or
• X and E can optionally be taken together to form a 4-7 membered substituted or unsubstituted ring wherein X is not nitrogen;
• or
• X and E can be taken together to form a 5-6 membered cycloalkyl or a 5-6 membered heterocyclyl;
• R11 is C1-C6 alkyl, —CF3, C5-C6 heteroaryl, or C5-C6 aryl;
• R12 is hydrogen, deuterium, C1-C6 alkyl, —OH, or —OR8;
• or
• R12 can be taken together with R1 to form a 4-7 membered saturated ring;
• and
• R13 is hydrogen;
• wherein R1, R2, and R12 are not all hydrogen;
• wherein R1 and R2 are not both ethyl;
• wherein R1 and R2 do not form a pyrrolidine ring;
• and
• wherein R1 and R12 do not form an imidazoline ring;
• or a pharmaceutically acceptable salt thereof.