# US 12,636,238 B2 · Hypochlorous acid-based eyelid cleansers

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- Number: US 12,636,238 B2
- Document ID: US12636238B2
- Status: Granted
- Kind: B2
- Application number: 18/756,974
- Filed: 2024-06-27
- Published: 2025-01-02
- Granted: 2026-05-26
- Earliest claimed: 2023-06-29
- Assignees: OCuSOFT, Inc.
- Applicants: OCuSOFT, Inc.
- Inventors: Paramita Sarkar
- Web page: https://patentgrep.com/patent/US12636238B2

## CPC

- A61K 8/20: Halogens; Compounds thereof
- A61K 8/36: Carboxylic acids; Salts or anhydrides thereof
- A61Q 19/10: Washing or bathing preparations
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

An antimicrobial eyelid cleanser composition contains hypochlorous acid, sodium acetate and purified water. The composition has a free available chlorine (FAC) concentration of from about 10 ppm-300 ppm, an osmolality of 40-200 mOsm/kg and a viscosity of 1 cP-500 cP. The composition has a pH from about 3.5-6.5. The eyelid cleanser composition is an ophthalmic or ocular composition that can clean the eyelids and eyes and remove excessive oil, debris, and desquamated skin from the eyelids and surrounding areas while reducing inflammation and promoting wound healing.

## Claims

### Claim 1

An eyelid cleanser composition comprising:
0.005 to 0.05 wt. % hypochlorous acid;
0.001 to 2.0 wt. % sodium acetate; and
purified water q.s. up to 100% w/w,
wherein the composition has a free available chlorine (FAC) concentration of from about 10 ppm-300 ppm.

### Claim 2 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition further comprises 0.05 wt. % to 0.75 wt. % sodium lauryl sulfate or sodium laureth sulfate.

### Claim 3 (depends on 2)

The eyelid cleanser composition according to claim 2, wherein the composition further comprises 0.001 wt. % to 2.0 wt. % acetic acid.

### Claim 4 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition further comprises 0.05 wt. % to 0.75 wt. % capryl/caprylyl glucoside.

### Claim 5 (depends on 4)

The eyelid cleanser composition according to claim 4, wherein the composition further comprises 0.05 wt. % to 1.0 wt. % propylene glycol.

### Claim 6 (depends on 5)

The eyelid cleanser composition according to claim 5, wherein the composition further comprises 0.001 wt. % to 2.0 wt. % acetic acid.

### Claim 7 (depends on 6)

The eyelid cleanser composition according to claim 6, wherein the composition further comprises 0.05 wt. % to 5.0 wt. % medium chain alkanes.

### Claim 8 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition further comprises 0.05 wt. % to 0.75 wt. % dioctyl sodium sulfocsuccinate.

### Claim 9 (depends on 8)

The eyelid cleanser composition according to claim 8, wherein the composition further comprises 0.001 wt. % to 2.0 wt. % acetic acid.

### Claim 10 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition has an osmolality of 40-200 mOsm/kg.

### Claim 11 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition has a viscosity of 1 cP-500 cP.

### Claim 12 (depends on 1)

The eyelid cleanser composition according to claim 1, wherein the composition has a pH from about 3.5-6.5.