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US 12,636,184 B2Granted
Schlemm's canal drug eluting device and method
AssigneeAlcon Inc.
InventorBrett A. Trauthen
Life of this patent
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Abstract
A method of delivering a pharmaceutical composition to Schlemm's canal of an eye is disclosed. The method may comprise inserting a drug delivery device in conjunction with a microstent into Schlemm's canal. The drug delivery device may comprise a bioerodable polymer and a pharmaceutical composition, and the drug delivery device may be configured to erode over time and to elute the pharmaceutical composition into aqueous humor within Schlemm's canal as it erodes.
Claims7
A method of delivering a pharmaceutical composition to Schlemm's canal of an eye, the method comprising:
- inserting a drug delivery device through an opening in trabecular meshwork into Schlemm's canal, the drug delivery device comprising a bioerodable polymer and the pharmaceutical composition, the drug delivery device being configured to erode over time and to elute the pharmaceutical composition into aqueous humor within Schlemm's canal as it erodes;
- inserting a microstent into Schlemm's canal, the microstent comprising an open central channel bordered in part by one or more wall supports, wherein inserting the microstent comprises inserting the microstent from an anterior chamber of the eye through the opening in the trabecular meshwork;
- supporting at least 4 mm of a longitudinal section of Schlemm's canal with the microstent;
- and
- allowing the drug delivery device to erode over time to elute the pharmaceutical composition into aqueous humor within Schlemm's canal as it erodes to dilate
- one or more of an outflow channel and an episcleral vein with the pharmaceutical composition.
3 more elements
Dependencies are inferred from the claim text.