Occluder, occluding system, and knotting method for tightening element in occluder

A knotting method for a tightening element of an occlude comprising:

• two occluding disks, configured for covering different openings of the defect;
• and
• a tightening element comprising a tightening thread, the tightening thread passing through the defect and being connected to the two occluding disks,
• wherein the tightening thread has a length between the two occluding disks, and the length is adjustable by means of a free end of the tightening thread;
• and
• wherein the tightening thread is formed by twisting and knotting a thread body, the thread body comprises a locking section, a first section, a second section and an adjusting section which are connected in sequence,
• the knotting method comprises the following steps:
• forming a thread loop by the first section to obtain a base thread loop;
• directing a remaining part of the first section to pass through the base thread loop to obtain a locking thread loop;
• directing the adjusting section to pass through a gap between the base thread loop and the locking thread loop in a first direction to obtain a reinforcing thread loop;
• and
• directing the adjusting section to pass through the locking thread loop such that the second section forms an adjusting thread loop between two occluding disks of the occluder, thereby obtaining the tightening thread,
• wherein the step of “directing the adjusting section to pass through the locking thread loop such that the second section forms an adjusting thread loop between two occluding disks of the occluder, thereby obtaining the tightening thread” specifically comprises:
• directing the adjusting section to pass through the locking thread loop in a second direction opposite to the first direction such that the second section forms the adjusting thread loop between the two occluding disks of the occluder, thereby obtaining the tightening element;
• wherein
• the first direction refers to a direction from the locking thread loop towards the base thread loop;
• or
• the first direction refers to a direction from the base thread loop to the locking thread loop.

A method of occluding an oval foramen in a heart of a patient with an occlude comprising:

• two occluding disks, configured for covering different openings of the defect;
• and
• a tightening element comprising a tightening thread, the tightening thread passing through the defect and being connected to the two occluding disks,
• wherein the tightening thread has a length between the two occluding disks, and the length is adjustable by means of a free end of the tightening thread;
• wherein the two occluding disks comprise a first occluding disk and a second occluding disk,
• the method comprising steps of:
• delivering the occluder into the heart of the patient;
• releasing the first occluding disk into a left atrium of the heart, and releasing the second occluding disk into a right atrium, with the tightening thread passing through the oval foramen;
• adjusting the length of the tightening thread between the first occluding disk and the second occluding disk such that tissues surrounding the oval foramen are clamped by the first occluding disk and the second occluding disk;
• and
• fixing the length of the tightening thread between the first occluding disk and the second occluding disk after adjusting the length of the tightening thread between the first occluding disk and the second occluding disk,
• wherein the tightening thread comprises an additional free end;
• and
• wherein the step of fixing the length of the tightening thread between the first occluding disk and the second occluding disk comprises driving the additional free end of the tightening thread.