Systems and methods for disease diagnosis
AssigneeRetispec Inc.
InventorsAdam James Gribble, Jared Lorne Westreich, Michael Frank Gunter Wood, Eliav Shaked, Alon Hazan
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Abstract
The present disclosure provides systems and methods for diagnosing disease. In some aspects, an imaging system is provided that includes a light source configured to illuminate a retina of the eye with light, one or more imaging devices configured to receive light returned from the retina to generate one or more spatial-spectral images of the retina, and a computing device configured to receive the one or more spatial-spectral images of the retina, evaluate the one or more spatial-spectral images, and identify one or more biomarkers indicative of a neurogenerative pathology.
Claims26
An imaging system comprising:
- a light source configured to illuminate a retina of an eye with light;
- one or more imaging devices configured to receive light returned from the retina to generate one or more spatial-spectral images of the retina;
- and
- a computing device configured to receive the one or more spatial-spectral images of the retina, extract segmented vessels of the retina from the one or more spatial-spectral images, evaluate the segmented vessels of the one or more spatial-spectral images, and identify one or more biomarkers indicative of a neurogenerative pathology along the segmented vessels or walls of the segmented vessels.
An imaging system comprising:
- a light source configured to illuminate a retina of an eye with light;
- one or more imaging devices configured to receive light returned from the retina to generate at least one spectral image and at least one spatial image of the retina;
- and
- a computing device configured to receive the at least one spectral image and at least one spatial image of the retina, extract segmented vessels of the retina from the at least one spectral image and at least one spatial image, evaluate the segmented vessels of the at least one spectral image and at least one spatial image, and identify one or more biomarkers indicative of a neurogenerative disease along the segmented vessels or walls of the segmented vessels.
A method for diagnosing a neurogenerative disease comprising:
- illuminating a retina of an eye with light with a light source;
- generating at least one spatial-spectral image by one or more imaging devices, the one or more imaging devices configured to receive light returned from the retina;
- extracting segmented vessels of the retina from the at least one spatial-spectral image;
- evaluating the segmented vessels of the at least one spatial-spectral image, the segmented vessels of the at least one spatial-spectral image being evaluated by a computing device configured to receive the at least one spatial-spectral image from the one or more imaging devices;
- and
- identifying one or more biomarkers indicative of a neurogenerative disease.
A method for diagnosing a neurogenerative disease comprising:
- obtaining, by a computer device, a retinal image mosaic comprising a plurality of spatial-spectral images from one or more regions of a retina;
- analyzing, by the computer device, the retinal image mosaic to extract segmented vessels of the retina from the plurality of spatial-spectral images;
- identify, from the segmented vessels, one or more biomarkers indicative of a neurogenerative pathology along the segmented vessels or walls of the segmented vessels;
- and
- generating, by the computer device, a digital representation indicative of a presence or absence of the one or more biomarkers in the one or more regions of a retina.
An imaging system comprising:
- a light source configured to illuminate a retina of an eye with light;
- one or more imaging devices configured to receive light returned from the retina to generate one or more spatial-spectral images of the retina;
- and
- a computing device configured to obtain a retinal image mosaic comprising the one or more spatial-spectral images from one or more regions of a retina, analyze the retinal image mosaic to extract segmented vessels of the retina from the one or more spatial-spectral images, identify, from the segmented vessels, one or more biomarkers indicative of a neurogenerative pathology, and generate a digital representation indicative of a presence or absence of the one or more biomarkers in the one or more regions of a retina.
Dependencies are inferred from the claim text.