Renal cancer detection method and test drug

A method of detecting and treating renal cancer in a subject, said method comprising:

• measuring the amount of tissue factor pathway inhibitor 2 (TFPI2) in a sample from the subject,
• detecting the subject having renal cancer when said measured amount of TFPI2 exceeds a predetermined standard value, and
• treating the subject detected with the renal cancer with a method for the treatment of the renal cancer selected from the group consisting of surgical resection, drug therapy, and radiation therapy,
• wherein the subject is a subject with suspected renal cancer or a subject under follow-up after definitive diagnosis of renal cancer,
• wherein the standard value is a measured value showing optimum sensitivity and specificity by measuring healthy individuals and renal cancers and analyzing receiver operating characteristic (ROC) curve,
• wherein the sample is serum or plasma, and
• the drug for the drug therapy is selected from the group consisting of tyrosine kinase inhibitors, mTOR inhibitors, and immune checkpoint inhibitors.