Isolation chip assembly

An isolation chip assembly configured for isolation and purification of target particles from a liquid sample, the isolation chip assembly comprising:

• an isolation chip, wherein the isolation chip comprises a sample reservoir, a first filtration membrane, and a second filtration membrane, the first filtration membrane and the second filtration member are disposed at opposite sides of the sample reservoir, sizes of pores of each of the first filtration membrane and the second filtration membrane are configured to be smaller than sizes of the target particles, the isolation chip further comprises a first chamber and a second chamber, the first chamber is connected to the sample reservoir through the first filtration membrane, the second chamber is connected to the sample reservoir through the second filtration membrane;
• first oscillators mounted on a surface of the first filtration membrane away from the sample reservoir and on a surface of the second filtration membrane away from the sample reservoir, wherein the first oscillators are configured to generate a first oscillation wave when operating;
• and
• second oscillators mounted on an of the first chamber away from the first filtration membrane and on an outer surface of the second chamber away from the second filtration membrane, wherein the second oscillators are configured to generate a second oscillation wave when operating, wherein the first oscillators and the second oscillators are located on a same horizontal plane, a frequency of the first oscillation wave is greater than a frequency of the second oscillation wave, an amplitude of the first oscillation wave is less than an amplitude of the second oscillation wave, and the first oscillation wave and the second oscillation wave are generated such that the first oscillation wave and the second oscillation wave cooperatively disturb the liquid sample, the first filtration membrane, and the second filtration membrane to generate an acoustic streaming;
• wherein the frequency of the first oscillation wave is 5000 Hz to 8000 Hz, and the frequency of the second oscillation wave is 100 Hz to 500 Hz.