Modified transglutaminase

A modified transglutaminase,

• wherein the modified transglutaminase exhibits a property change corresponding to the an amino acid substitution,
• the property changes due to the amino acid substitution are a reduction in temperature stability and an improvement in oxidation resistance,
• the modified transglutaminase has an amino acid sequence comprising the amino acid sequence of SEQ ID NO:
• 1 with any one of the following amino acid substitutions (1) to (10), or an amino acid sequence showing having 90% or more sequence identity to the amino acid sequence of SEQ ID NO:
• 1 with the amino acid substitutions (1) to (10), provided that a difference in the amino acid sequence occurs at a portion other than the position of the amino acid substitution:
• (1) an amino acid substitution at residue V6, the amino acid after substitution is P;
• (2) an amino acid substitution at residue R26, the amino acid after substitution is K, Q, M, Y, D, G, N, P or H;
• (3) an amino acid substitution at residue E28, the amino acid after substitution is V, R, K, M, N, F, G, L or Y;
• (4) an amino acid substitution at residue Y42, the amino acid after substitution is F, L or M;
• (5) an amino acid substitution at residue E58, the amino acid after substitution is Y, M, A, F, I, V, R, K, L or Q;
• (6) an amino acid substitution at residue V67, the amino acid after substitution is A or S;
• (7) an amino acid substitution at residue T68, the amino acid after substitution is C, L or M;
• (8) an amino acid substitution at residue T77, the amino acid after substitution is C;
• (9) an amino substitution at residue T273, the amino acid after substitution is E;
• and
• (10) an amino acid substitution at residue Y291, the amino acid after substitution is I, L, C, N, S or V.