Medical device with tunable hydrophobicity and method of manufacture

A medical device having a first region and a second region, the medical device comprising:

• a polyurethane layer comprising a plurality of monomer residues, the polyurethane layer extending through the first region and the second region;
• wherein at least some of the plurality of monomer residues include a chain extender molecule with a pendent alkene group;
• wherein the chain extender molecule comprises a residue of one or more of:
• a first hydro-specific layer covalently bonded to the polyurethane layer within the first region;
• and
• a second hydro-specific layer covalently bonded to the polyurethane layer within the second region.

A medical device, comprising:

• a polyurethane layer formed to include a plurality of pendent functional chemical handles;
• wherein the polyurethane layer include a chain extender molecule having the plurality of pendent functional chemical handles;
• wherein the chain extender molecule comprises a residue of one or more of:
• a hydro-specific layer covalently bonded to the polyurethane layer, the hydro-specific layer including a plurality of hydro-specific molecules covalently bonded to the plurality of pendent functional chemical handles.