Binding molecules specific for CD73 and uses thereof

An isolated binding molecule which specifically binds to CD73 selected from:

• (a) an antibody having a VH CDR1 comprising SEQ ID NO:
• 35, a VH CDR2 comprising SEQ ID NO:
• 95, a VH CDR3 comprising SEQ ID NO:
• 96, a VL CDR1 comprising SEQ ID NO:
• 97, a VL CDR2 comprising SEQ ID NO:
• 99, and a VL CDR3 comprising SEQ ID NO:
• 100;
• (b) an antibody having a VH comprising SEQ ID NO:
• 87 and a VL comprising SEQ ID NO:
• 88;
• or
• (c) an antibody having a VH CDR1 comprising SEQ ID NO:
• 35, a VH CDR2 comprising SEQ ID NO:
• 95, a VH CDR3 comprising SEQ ID NO:
• 96, a VL CDR1 comprising SEQ ID NO:
• 97, a VL CDR2 comprising SEQ ID NO:
• 99, and a VL CDR3 comprising SEQ ID NO:
• 100, wherein the VH domain comprises a sequence 95%, 96%, 97%, 98%, or 99% similar to the VH of SEQ ID NO:
• 87, and wherein the VL domain comprises a sequence 95%, 96%, 97%, 98%, or 99% similar to the VL of SEQ ID NO:
• 88.