Method of killing leukemia cells by administration of recombinant'Y3 proteins
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsYousong Ding, Peilan Zhang, Steven Douglas Bruner
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Abstract
The subject invention pertains to compositions and methods for preparing and using recombinant proteins based on the fungal Coprinus comatus Y3 protein to control plant and animal viruses and microbes, and diagnose, prevent and treat cancers. Methods are disclosed using compositions comprising recombinant Y3 proteins to diagnose, prevent and/or treat cancer diseases based on recombinant Y3 protein interaction with glycans expressed on cancer cells.
Claims12
A method of killing leukemia cells in a subject, the method comprising:
- administering to a subject having leukemia a composition comprising a recombinant Y3 protein, wherein the recombinant Y3 protein comprises the sequence set forth in SEQ ID NO:
- 3 and lacks amino acid residues 1-18 of SEQ ID NO:
- 1.
A method of killing leukemia cells in a subject, the method comprising:
- administering to a subject having leukemia a composition comprising a recombinant Coprinus comatus Y3 protein consisting of amino acid residues 24 to 126 of SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.