Compounds

A compound of formula (I):

• wherein:
• R1a is H or methyl;
• R1b is H or F;
• A is group (Aa), (Ab), (Ac) or (Ad):
• wherein group (Aa) is:
• wherein:
• R2 is H, C1-4alkyl, C1-4alkylene(aryl), C1-4alkylene(OH), C1-4alkylene(C3-6cycloalkyl), C1-4alkylene (4-7 membered heterocycloalkyl), C1-4alkoxy, OC1-4alkylene(aryl), C1-4alkyleneOC1-4alkyl, C1-4alkyleneOC3-6cycloalkyl, C1-4alkyleneO(4-7 membered heterocycloalkyl), C1-4alkyleneO(aryl), C3-6alkynyl or C1-4alkenylO(C3-6alkynyl);
• wherein said aryl, heterocycloalkyl and cycloalkyl are optionally substituted by 1, 2 or 3 substituents each independently selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, halo, CN, OH, NR2aR2b, SO2R2c and NHSO2R2c;
• R2a is selected from H and C1-4alkyl;
• R2b is selected from H, C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R2c is selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• each R3 is independently halo, methyl, ethyl or n-propyl;
• m is 0, 1, 2, 3 or 4;
• wherein group (Ab) is:
• wherein:
• R4 is H, C1-4alkyl or C1-4alkylene(aryl);
• wherein said aryl is optionally substituted by 1, 2 or 3 substituents each independently selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, halo, CN, OH, NR4aR4b, SO2R4c and NHSO2R4c;
• R4a is selected from H and C1-4alkyl;
• R4b is selected from H, C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R4c is selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R5 is H or C1-4alkyl;
• each R6 is independently C1-4alkyl or halo;
• n is 0, 1, 2 or 3;
• wherein group (Ac) is:
• wherein:
• R7 is C1-4alkyl, C1-4alkylene(OH) or C1-4alkyleneOC1-4alkyl;
• is 1 or 2;
• wherein group (Ad) is:
• wherein:
• X is a bond, O or CH2;
• each R8 is independently halo, C1-4alkyl, C1-4alkoxy, OC1-4haloalkyl, OC1-4alkylene(C3-6cycloalkyl), OC1-4alkylene (4-7 membered heterocycloalkyl) or OH;
• wherein said heterocycloalkyl and cycloalkyl are optionally substituted by 1, 2 or 3 substituents independently selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, halo, CN, OH, NR8aR8b, SO2R8c and NHSO2R8c;
• R8a is selected from H and C1-4alkyl;
• R8b is selected from H, C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R8c is selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• each R9 is independently halo or C1-4alkyl;
• p is 0, 1 or 2;
• q is 0, 1, 2, 3 or 4;
• wherein B is group (Ba), (Bb) or (Bc):
• wherein group (Ba) is:
• wherein:
• Y is C(R11)(R12), N(R13), O or S;
• each R10 is independently halo or C1-4alkyl;
• r is 0, 1, 2 or 3;
• R11 is H or C1-4alkyl;
• R12 is H or C1-4alkyl;
• or R11 and R12 together with the carbon atom to which they are attached form a C3-6cycloalkyl;
• R13 is H, C1-4alkyl or C3-6cycloalkyl;
• wherein said cycloalkyl is optionally substituted by 1, 2 or 3 substituents independently selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, halo, CN, OH, NR13aR13b, SO2R13c and NHSO2R13c;
• R13a is selected from H and C1-4alkyl;
• R13b is selected from H, C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R13c is selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• wherein group (Bb) is:
• wherein:
• each R14 is independently halo or C1-4alkyl;
• sis 0, 1, 2 or 3;
• wherein group (Bc) is:
• wherein:
• R15 is C1-4alkyl, C1-4alkoxy, C3-6cycloalkyl, C1-4haloalkyl, halo or CN;
• wherein said cycloalkyl is optionally substituted by 1, 2 or 3 substituents independently selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, halo, CN, OH, NR15aR15b, SO2R15c and NHSO2R15c;
• R15a is selected from H and C1-4alkyl;
• R15b is selected from H, C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R15c is selected from C1-4alkyl, C3-6cycloalkyl, C1-4alkoxy, C1-4haloalkyl, aryl and 4-7 membered heterocycloalkyl;
• R16 is H, halo or C1-4alkyl;
• and
• D, E and F are each independently C(R16);
• or one of D, E and F is N, and the two remaining D, E and F groups are independently C(R16);
• or a pharmaceutically acceptable salt and/or solvate thereof.