Phenethylamine derivatives, compositions, and methods of use
AssigneeCybin IRL Limited
InventorsAlex Belser, Clinton E. Canal, Brett J. Greene, Joshua A. Hartsel, Alex Nivorozhkin, Michael Palfreyman, Francesco Salituro
Life of this patent
Estimating the term…
Abstract
There are disclosed psychedelic and entactogen compounds, the use of such compounds in the treatment of diseases associated with a serotonin 5-HT2 receptor, pharmaceutical compositions such as tablet compositions and kits containing the compounds, methods of delivering the compounds in a mist via inhalation, and methods of treating diseases or disorders associated with a serotonin 5-HT2 receptor, such as central nervous system (CNS) disorders or psychological disorders with the compounds of the invention.
Claims20
A compound having a structure of formula (II):
- or a pharmaceutically acceptable salt, solvate, stereoisomer, or prodrug thereof,
- wherein:
- X1 and X2 are independently hydrogen, deuterium, or a substituted or unsubstituted C1-C6 alkyl;
- Y1 and Y2 are independently hydrogen, deuterium, or a substituted or unsubstituted C1-C6 alkyl;
- R2 and R3 are independently hydrogen, deuterium, halogen, a substituted or unsubstituted C1-C6 alkyl, —ORa, or —SRa;
- R6 and R7 are independently hydrogen, an unsubstituted C1-C6 alkyl, or a C1-C6 alkyl substituted with one or more deuterium;
- each Ra is independently hydrogen, deuterium, or a substituted or unsubstituted C1-C6 alkyl;
- A is S;
- and
- Z1 and Z2 are independently deuterium, or fluorine.
Dependencies are inferred from the claim text.