Back to results
US 12,629,696 B2Granted
Dielectric materials
AssigneeXzom, Inc.
InventorsJuan Pablo Hinestrosa Salazar, Rajaram Krishnan, Scott Conradson, Tyler Lee Harris, Robert Paul Turner, George Maroor Thomas
Life of this patent
Estimating the term…
Abstract
The present disclosure describes methods, devices and systems comprising materials comprising dielectrics. In various aspects, electrodes layered or imbedded with these dielectrics provide enhanced properties for a wide range of applications, such as the enhanced separation of analytes, such as biological molecules or particles (nucleic acids, viruses) with an electrokinetic field.
Claims40
A method of diagnosing a disease or condition in a patient comprising:
- (a) applying a sample to a device to capture a plurality of analytes in the sample, wherein the device comprises an electrode configured to generate an electrokinetic force;
- and a layer in contact with at least a portion of the electrode, wherein the layer comprises a dielectric material of about 5 angstroms to about 25 angstroms in thickness, wherein the device increases the total yield of analyte captured as compared to a device that lacks a layer or has a layer that is more than 25 angstroms in thickness;
- (b) detecting the plurality of analytes captured;
- and
- (c) comparing an amount of each of the plurality of analytes in the sample to a respective known standard to diagnose the disease or condition in the patient.
2 more elements
A method of monitoring a disease or condition in a patient comprising:
- (a) applying a sample to a device to capture a plurality of analytes in the sample, wherein the device comprises an electrode configured to generate an electrokinetic force;
- and a layer in contact with at least a portion of the electrode, wherein the layer comprises a dielectric material of about 5 angstroms to about 25 angstroms in thickness, wherein the device increases the total yield of analyte captured as compared to a device that lacks a layer or has a layer that is more than 25 angstroms in thickness;
- (b) detecting the plurality of analytes captured;
- and
- (c) measuring an amount of each of the plurality of analytes in the sample to monitor the disease or condition in the patient.
2 more elements
Dependencies are inferred from the claim text.