Non-contact, on-slide fluid mixing
AssigneeVentana Medical Systems, Inc.
InventorsEmily Alkandry, Anik Duttaroy, Evan Graves
Life of this patent
Estimating the term…
Abstract
A microscope slide holder comprising a slide support member and at least one acoustic source for introducing acoustic waves to a microscope slide in communication with the slide support member such that one or more fluids present on the surface of the microscope slide are contactlessly mixed.
Claims22
An apparatus comprising one or more support members and at least one acoustic source, wherein the at least one acoustic source is configured to introduce low frequency vibrations to a substrate disposed on the one or more support members such that one or more fluids and/or reagents present on a surface of the substrate are contactlessly moved or distributed, wherein the at least one acoustic source is in direct contact with at least a portion of the one or more support members.
A method of processing a substrate comprising:
- (i) introducing at least one fluid or reagent to a sample disposed on a surface of the substrate;
- and (ii) distributing the at least one fluid or reagent on the surface of the substrate by introducing low frequency acoustic waves from at least one acoustic source to the substrate, wherein the low frequency acoustic waves have a frequency that will not damage cells, wherein the at least one acoustic source is in direct contact with at least a portion of a one or more support members, where each of the one or more support members is in physical contact with the substrate.
An apparatus comprising one or more support members and at least one acoustic source, wherein the at least one acoustic source is configured to introduce low frequency vibrations to a substrate disposed on the one or more support members such that one or more fluids and/or reagents present on a surface of the substrate are contactlessly moved or distributed, wherein the at least one acoustic source operates at a frequency ranging from between about 1 Hz to about 1 kHz.
Dependencies are inferred from the claim text.