Devices and methods for delivering synergistic active agents to target sites
AssigneeIRRIMAX Corporation
InventorsPaul Rucinski, Michael A. Gil, Venkata Katragadda
Life of this patent
Estimating the term…
Abstract
Novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation are described herein. Methods and devices disclosed herein utilize a synergistic combination of two or more antiseptic agents to reduce contact time, enhance antimicrobial effects, and reduce the likelihood of allergy and other side effects from the antiseptic agents in subjects. In one embodiment, devices include a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.
Claims19
A method for irrigating a wound comprising the steps of:
- (a) providing a non-sterile or sterile wound irrigation solution in a wound irrigation device comprising a reservoir housing, wherein the wound irrigation device comprises a discharge means that directs a pressurized stream of the wound irrigation solution when the reservoir housing is pressurized, and wherein the wound irrigation solution comprises (i) sterile water, purified water, or water for pharmaceutical purposes;
- (ii) a chlorhexidine at a concentration that is between about 100 μg/mL to about 5 mg/mL, and (iii) lauroyl arginate ethyl ester (LAE) or a pharmaceutically acceptable salt thereof at a concentration that is between about 1 μg/mL to about 200 μg/mL;
- (b) directing the discharge means and the reservoir housing so as to discharge the wound irrigation solution toward the wound;
- and
- (c) discharging a stream of the wound irrigation solution from the reservoir housing and through the discharge means directed at the wound.
Dependencies are inferred from the claim text.