Agent to be used in intraocular membrane detachment surgery
AssigneesFukuoka University, Seikagaku Corporation
InventorsToshio Hisatomi, Kiyoshi Suzuki
Life of this patent
Estimating the term…
Abstract
An object of the present invention is to find a useful means for removing an intraocular membrane. The present invention relates to an agent for use in intraocular membrane peeling surgery, which contains a solution containing a hydrogel-forming material and satisfies the following formula 1 with respect to the dynamic viscoelasticity measured at a temperature of 25 to 40° C. and a frequency of 1 Hz. 0<Vmax≤3 (Formula 1) Provided that in the formula 1, Vmax (Pa/sec) is the maximum change rate of the storage elastic modulus after the initiation of gelation.
Claims19
A method for peeling an intraocular membrane, comprising applying an agent comprising a solution comprising a hydrogel-forming material onto an intraocular membrane of a patient, and
- peeling the intraocular membrane together with a hydrogel adhered to the intraocular membrane,
- wherein the agent satisfies the following formula 1 with respect to the dynamic viscoelasticity measured at a temperature of 25 to 40° C. and a frequency of 1 Hz:
- 0<Vmax≤3, (Formula 1)
- wherein Vmax (Pa/sec) is the maximum change rate of the storage elastic modulus after the initiation of gelation,
- wherein the hydrogel-forming material comprises two or more types of compounds, and
- wherein the gelation is caused by a crosslinking reaction initiated by mixing the two or more types of compounds.
A method for peeling an intraocular membrane, comprising injecting a solution comprising a hydrogel-forming material into an eye of a patient to form a crosslinked hydrogel adhered to the intraocular membrane, and peeling the intraocular membrane together with the hydrogel.
Dependencies are inferred from the claim text.