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AssigneeMusculoskeletal Transplant Foundation
InventorsBenjamin Schilling, Andrew Madans, Abigail Phipps, Thomas Tylutki, Todd Nilsen, Yen-Chen Huang, Evangelia Chnari
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Compositions including a first soft tissue-derived matrix and a second soft tissue-derived matrix are provided, as well as methods of making such compositions. In some embodiments, the composition comprises delipidated, decellularized adipose tissue-derived matrix and delipidated, decellularized fascial tissue-derived matrix, which may be combined in various proportions. Such adipose-fascia matrix compositions provide improved volume retention when implanted into a patient. The composition may further include exogenous cells or other substances, and/or a carrier. The composition is suitable for use in plastic surgery procedures, including reconstructive or cosmetic surgery procedures, as well as procedures for wound treatment and tissue regeneration. The methods for making the compositions may involve separation of first and second soft tissues from one another, followed by performing one or more treatments on the separated soft tissues, then combining the treated soft tissues and, optionally, performing one or more additional treatments on the combined soft tissues.
A method for increasing, enhancing, or improving volume retention at a region to be treated in a patient, comprising a step of implanting a composition in, on, or proximate to the region to be treated in the patient, thereby forming an implantation site, wherein the composition comprises:
A method for cosmetic or reconstructive surgery on a patient having a region to be treated, comprising a step of implanting in, on, or proximate to the region to be treated, thereby forming an implantation site, a composition comprising:
A method for treatment of a wound site or tissue atrophy site of a patient, comprising a step of implanting, into, on, around, proximate to, or under the wound site or tissue atrophy site, a composition comprising:
Dependencies are inferred from the claim text.