Disinfecting cap for male and female connectors

A cap configured to engage a male connector and a female connector, comprising:

• a first housing for the female connector comprising a closed bottom, an open top, and a sidewall extending between the bottom and the top;
• a first absorbent support disposed in the first housing configured to contact portions of the female connector;
• a removable second housing for the male connector disposed in the first housing, the second housing comprising a bottom, a top, and a sidewall extending between the bottom and the top with an outer surface of the sidewall of the second housing engaged to an inner surface of the sidewall of the first housing, the second housing contacts and compresses the first absorbent support, when the second housing is removed from the first housing, the first absorbent support expands such that a top surface of the first absorbent support extends towards the open top of the first housing;
• a second absorbent support disposed in the removable second housing configured to contact portions of the male connector;
• and
• a protective cover is removably mounted to the open top of the first housing by heat sealing, the protective cover is configured to protect the inner surface of the sidewall of the first housing, the outer surface of the second housing, and the first absorbent support and the second absorbent support.