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US 12,629,413 B2Granted
Utilizing vaccines to treat cancer and enhance the success rate of cancer immunotherapy
AssigneeRush University Medical Center
InventorsAndrew Zloza, Jenna H. Newman
Life of this patent
Estimating the term…
Abstract
Methods treating cancer are provided. The methods include intratumorally administering a therapeutically effective dose of a vaccine to a subject in need thereof.
Claims19
A method of treating cancer in a subject in need thereof comprising:
- intratumorally administering a therapeutically effective dose of an inactivated influenza vaccine to the subject,
- wherein the cancer is selected from the group consisting of melanoma, lung, triple-negative breast, or renal;
- and
- wherein the vaccine is unadjuvanted.
1 more element
A method of increasing an immune response in a tumor in a subject in need thereof, the method comprising:
- intratumorally administering a therapeutically effective dose of an inactive influenza vaccine to the subject,
- wherein the tumor is a melanoma tumor, a lung tumor, a triple-negative breast cancer tumor, or a kidney tumor.
A method of treating cancer in a subject in need thereof comprising:
- intratumorally administering a therapeutically effective dose of an inactivated vaccine to the subject,
- wherein the inactivated vaccine is selected from the group consisting of DTaP (diphtheria, pertussis, and tetanus), pneumococcal polysaccharide vaccine (Pneumococcal Pneumonia), HepB (hepatitis B), and MMR (measles, mumps, rubella);
- wherein the cancer is selected from the group consisting of melanoma or colon cancer;
- and
- wherein the vaccine is unadjuvanted.
2 more elements
Dependencies are inferred from the claim text.