Microdialysis system comprising flow feedback device

A microdialysis system comprising a flow rate feedback device, wherein the system comprises:

• a perfusion device (1), a first connecting pipeline (2), a second connecting pipeline (3), and the flow rate feedback device (4);
• the flow rate feedback device (4) comprising a connecting needle (41), a liquid collection container (42), a calibration weighing module (43), and a flow rate feedback control display module (44);
• wherein the perfusion device (1) comprises a micropump and a syringe, and the micropump pumps dialyzable substances into the first connecting pipeline (2) through the syringe;
• one end of the first connecting pipeline (2) is fluidly connected to the syringe, and the other end of the first connecting pipeline (2) is fluidly connected to an inlet of a microdialysis probe, the first connecting pipeline (2) is configured to transport dialyzable substances to the microdialysis probe, so that the dialyzable substances enter a living organism through the microdialysis probe;
• the second connecting pipeline (3) is configured to transport dialysate from the living organism to the flow rate feedback device (4), one end of the second connecting pipeline (3) is fluidly connected to an outlet of the microdialysis probe, and the other end of the second connecting pipeline (3) is fluidly connected to the connecting needle (41);
• the liquid collection container (42) is provided below the connecting needle (41) and configured to collect dialysate from the living organism;
• the calibration weighing module (43) is configured to regularly measure weight of a liquid in the liquid collection container (42) according to conditions and programs set in the flow rate feedback control display module (44), and transmit a measured liquid weighing value to the flow rate feedback control display module (44);
• and
• the flow rate feedback control display module (44) performs a difference operation between a current liquid weighing value and a previous liquid weighing value to obtain a weighing sampling difference, and compares the weighing sampling difference with a predetermined value to monitor whether the connecting needle (41) is discharging liquid normally, and thus gives a feedback on a state of flow rate of the liquid in the first connecting pipeline (2) and the second connecting pipeline (3).