Back to results
US 12,628,857 B2Granted
Compositions comprising human milk oligosaccharides for use in a subject to support night sleep duration
AssigneeSociete des Produits Nestle S.A.
InventorsClara Lucia Garcia-Rodenas, Jonas Hauser, Weili Lin, Ziliang Zhu, Seoyoon Cho, Tengfei Li
Life of this patent
Estimating the term…
Abstract
The present invention relates to a nutritional composition comprising at least one human milk oligosaccharide comprising 3′ sialyllactose (3-SL), lacto-N-tetraose (LNT), core-HMOs and any combination thereof for improving improving total night sleep duration in a subject.
Claims11
A method for improving total night sleep duration or sleep quality in a subject in need thereof, the method comprising administering to the subject a nutritional composition comprising at least one human milk oligosaccharide,
- wherein the at least one human milk oligosaccharide is present in a total amount of 50 mg to 2500 mg/L of the nutritional composition, and
- the total sleep night duration or sleep quality is assessed on the basis of a questionnaire to quantify quantity and quality of sleep (BISQ),
- the subject is an infant or young child that is small for gestational age (SGA) or was born preterm, and
- the at least one human milk oligosaccharide comprises one of
- (i) a mixture of lacto-N-neotetraose (LNnT), lacto-N-tetraose (LNT), and para-lacto-N-neohexaose;
- (ii) a combination of 3′ sialyllactose (3-SL) and lacto-N-tetraose (LNT);
- or
- (iii) a combination of 3′ sialyllactose (3-SL) and a mixture of lacto-N-neotetraose (LNnT), lacto-N-tetraose (LNT), and para-lacto-N-neohexaose.
5 more elements
Dependencies are inferred from the claim text.