Photonic biosensors for multiplexed diagnostics and a method of use

A method of use of photonic biosensors for multiplexed diagnostics, the method comprising:

• obtaining a portable device comprising a disposable microfluidic cartridge, wherein the disposable microfluidic cartridge comprises at least a fluid, wherein the at least a fluid comprises one or more analytes and wherein the disposable microfluidic cartridge comprises:
• a photonic sensor chip, the photonic sensor chip comprising:
• one or more resonators substantially in contact with the at least a fluid, wherein the portable device is configured for point-of-care diagnostics, wherein the one or more resonators comprises a plurality of ring resonators, wherein a gap exists between the plurality of ring resonators and an optical waveguide;
• and
• a microfluidic assembly situated atop the one or more resonators and located along a surface of the photonic sensor chip;
• detecting, using a first ring resonator of the plurality of ring resonators, a first analyte of the one or more analytes of the at least a fluid;
• detecting, using a second ring resonator of the plurality of ring resonators, a second analyte of the one or more analytes of the at least a fluid, wherein the second analyte is different from the first analyte;
• providing, using at least a light source of a reader device of the portable device communicatively connected to the photonic sensor chip, an input optical signal to the photonic sensor chip;
• providing a connecting system to connect the photonic sensor chip and the reader device, wherein the connecting system comprises a multi-fiber push-on (MPO) connector;
• receiving, using the reader device, one or more sensor signals from the photonic sensor chip;
• and
• determining, using the reader device, one or more characteristics of the first analyte and the second analyte of the one or more analytes of the at least a fluid as a function of the one or more sensor signals provided by the photonic sensor chip including the first ring resonator and the second ring resonator.