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US 12,625,136 B2Granted
Sensor device
AssigneeImec Vzw
InventorsWillem Van Roy, Tim Stakenborg, Kris Covens
Life of this patent
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Abstract
A device (1) for sensing an analyte, the device (1) comprises at least a sample inlet (10) for receiving a sample, affinity probes (111) selected to have a preferential binding to the analyte, a transducer (11) sensitive to a characteristic of the analyte and/or a label attached to the analyte, the transducer not being a FET transducer, and a desalting unit (13) for desalting the received sample.
Claims12
A method for measuring a concentration of an analyte in a biological sample, the method comprising:
- receiving a biological sample;
- coupling the sample to affinity probes and a transducer;
- desalting the sample, wherein desalting the sample comprises performing electrodialysis on the affinity probes and the transducer;
- measuring at least one signal of the sample by means of an affinity-based sensing device based on the affinity probes and the transducer, the transducer not being a Field Effect Transistor transducer;
- and
- determining the concentration of the analyte in the sample using the at least one signal.
3 more elements
Dependencies are inferred from the claim text.