Polypeptide improved in protein purity and affinity for antigen, conjugate thereof with antibody or antigen-binding fragment, and preparation method therefor
AssigneeAbclon Inc.
InventorsJong Ho Lee, Hyun Jong Lee, Bong Kook Ko, Kyu Tae Kim, Jong Seo Lee
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Abstract
The present invention relates to a polypeptide improved in protein purity and in affinity for a target antigen, a conjugate thereof with an antibody or antigen-binding fragment, and a preparation method of the polypeptide and the conjugate. The polypeptide or the conjugate thereof according to the present invention does not undergo glycosylation even when produced in a eukaryotic cell and thus has high protein purity and affinity for a target antigen, showing a very high value as a reagent for diagnosis or treatment of a disease.
Claims10
A polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs:
- 2, 3, and 4.
Dependencies are inferred from the claim text.