SMARCA degraders and uses thereof

A compound of any one of the following formulae formula:

• or a pharmaceutically acceptable salt thereof, wherein:
• L is,
• each R is independently hydrogen or C1-6 aliphatic;
• and
• DIM is a compound of formula I-a:
• or a pharmaceutically acceptable salt thereof, wherein:
• X1 is —C(O)—;
• X2 is a carbon atom or silicon atom;
• X3 is —CR2-;
• R1 is hydrogen or C1-4 aliphatic;
• each R2 is independently hydrogen, R6, halogen, —CN, or —OR;
• Ring A is a bicyclic ring selected from
• Ring B is a fused ring selected from 6-membered aryl, 6-membered heteroaryl containing 1-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur, 5 to 7-membered saturated or partially unsaturated carbocyclyl, 5 to 7-membered saturated or partially unsaturated heterocyclyl with 1-3 heteroatoms independently selected from boron, nitrogen, oxygen, silicon, or sulfur, or 5-membered heteroaryl with 1-4 heteroatoms independently selected from nitrogen, oxygen or sulfur;
• R3 is hydrogen;
• each R4 is independently hydrogen or R6;
• each R6 is independently a group selected from C1-6 aliphatic, phenyl, a 4-7 membered saturated or partially unsaturated heterocyclic ring having 1-2 heteroatoms independently selected from nitrogen, oxygen, and sulfur, and a 5-6 membered heteroaryl ring having 1-4 heteroatoms independently selected from nitrogen, oxygen, and sulfur;
• L1 is a covalent bond;
• and
• m is 0, 1, 2, 3 or 4.