Fabrication of aquaporin-based biomimetic membrane
AssigneeNanyang Technological University
InventorsRong Wang, Saren Qi, Ye Li
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Abstract
Methods of fabricating a membrane comprising proteoliposomes having protein water channels are provided herein. The method may include providing a porous substrate, depositing a solution containing proteoliposomes on the porous substrate, and then contacting the porous substrate with an aqueous monomer solution and an organic monomer solution to form a selective layer on the porous substrate embedding the proteoliposomes. The method may include depositing the aqueous monomer solution, then the solution containing the proteoliposomes, then the organic monomer solution, to form the selective layer. The present disclosure also describes the membrane and a system operable to accommodate both methods.
Claims13
A method of fabricating a membrane comprising proteoliposomes having protein water channels, the method comprising:
- providing a porous substrate;
- spraying a solution comprising the proteoliposomes on the porous substrate to cover a surface of the porous substrate with the proteoliposomes;
- drying the porous substrate having the solution deposited thereon to form a porous substrate having a layer of proteoliposomes deposited directly thereon;
- contacting the porous substrate having the layer of proteoliposomes deposited directly thereon with an aqueous monomer solution followed by an organic monomer solution;
- and
- carrying out interfacial polymerization on the aqueous monomer solution and the organic monomer solution to form a selective layer covering the layer of proteoliposomes on the porous substrate.
Dependencies are inferred from the claim text.