Process for testing filters
AssigneeGambro Lundia AB
InventorsClaudia Assmann, Ralf Flieg, Wolfgang Freudemann, Torsten Knoer, Mehmet Yildirim
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Abstract
The present disclosure relates to a process for testing the integrity of membranes in a filter module. Specifically, the process is applied to filters for extracorporeal blood treatment, in particular, filters comprising both filter membranes and particulate material.
Claims19
A process for identifying damage to a filter comprising a first compartment and a second compartment, wherein the first compartment and the second compartment are separated by a porous membrane, said process comprising the steps of:
- i) providing the filter, wherein the first compartment of the filter and the second compartment of the filter are both filled with a testing liquid;
- ii) establishing a pressure gradient between the first compartment and the second compartment by introducing a testing gas into the first compartment, thus displacing the testing liquid from the first compartment;
- iii) evaluating the filter via a) monitoring the pressure gradient established in step ii), b) measuring flow of the testing gas through the porous membrane separating the first compartment and the second compartment, or c) both;
- wherein the testing liquid is an aqueous solution of sodium chloride comprising a salt concentration in the range of from about 10 wt. % to about 20 wt. %;
- and
- wherein the testing gas is air.
A process for identifying damage to a filter comprising a first compartment and a second compartment, wherein the first compartment and the second compartment are separated by a porous membrane, said process comprising the steps of:
- i) providing the filter, wherein the first compartment of the filter and the second compartment of the filter are both filled with a testing liquid;
- ii) establishing a pressure gradient between the first compartment and the second compartment by introducing a testing gas into the first compartment, thus displacing the testing liquid from the first compartment;
- iii) evaluating the filter via a) monitoring the pressure gradient established in step ii), b) measuring flow of the testing gas through the porous membrane separating the first compartment and the second compartment, or c) both;
- wherein the testing liquid is an aqueous solution of sodium chloride comprising a salt concentration of about 10 wt. %;
- and
- wherein the testing gas is air.
A process for identifying damage to a filter comprising a first compartment and a second compartment, wherein the first compartment and the second compartment are separated by a porous membrane, said process comprising the steps of:
- i) providing the filter, wherein the first compartment of the filter and the second compartment of the filter are both filled with a testing liquid;
- ii) establishing a pressure gradient between the first compartment and the second compartment by introducing a testing gas into the first compartment, thus displacing the testing liquid from the first compartment;
- iii) evaluating the filter via a) monitoring the pressure gradient established in step ii), b) measuring flow of the testing gas through the porous membrane separating the first compartment and the second compartment, or c) both;
- wherein the testing liquid is an aqueous solution of sodium chloride comprising a salt concentration of about 20 wt. %;
- and
- wherein the testing gas is air.
Dependencies are inferred from the claim text.