Implantable pump for direct sodium removal therapy having on-board analyte sensor
AssigneeDSRCo BV
InventorsIan Crosbie, Andreas Wirth, Oliver Goedje
Life of this patent
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Abstract
Systems and methods for performing Direct Sodium Removal (DSR) therapy are provided in which an implantable device includes a pump coupled to an inlet catheter designed for placement in a patient's peritoneal cavity, an outlet catheter designed to be coupled to the patient's bladder, and is operably coupled to an analyte sensor, the pump programmed to transfer and/or cease transfer of fluid from the patient's peritoneal cavity to the patient's bladder for voiding responsive to a level of analyte detected by the analyte sensor. In addition, the system may include a processor that computes an amount of analyte transferred per pumping session.
Claims21
A system for use with a direct sodium removal (DSR) solution for conducting direct sodium removal therapy in a patient, the system comprising:
- an infusate configured to be introduced into a peritoneal cavity, the infusate comprising a solution having a sodium content less than 35 meq/L and (i) from 0.5 to 50 grams dextrose per 100 ml of aqueous solution, (ii) from 0.5 to 50 grams icodextrin/dextrin per 100 ml of aqueous solution, and (iii) purified water;
- an analyte sensor configured to output a signal indicative of an analyte concentration associated with the infusate introduced into the peritoneal cavity;
- and
- a processor coupled to the analyte sensor and configured to receive the signal indicative of the analyte concentration.
A system for use with a direct sodium removal (DSR) solution for conducting direct sodium removal therapy in a patient, the system comprising:
- an infusate configured to be introduced into a peritoneal cavity, the infusate being a solution with a sodium content less than 35 meq/L and consisting of 0.5 to 50 grams dextrose per 100 ml of aqueous solution, 0.5 to 50 grams icodextrin/dextrin per 100 ml of aqueous solution, and purified water;
- an analyte sensor configured to output a signal indicative of an analyte concentration associated with the infusate introduced into the peritoneal cavity;
- and
- a processor coupled to the analyte sensor and configured to receive the signal indicative of the analyte concentration.
A method of performing direct sodium removal (DSR) therapy to remove excess sodium from a patient to reduce fluid overload, the method comprising:
- introducing an infusate into a peritoneal cavity, the infusate comprising a solution having a sodium content less than 35 meq/L and (i) from 0.5 to 50 grams dextrose per 100 ml of aqueous solution, (ii) from 0.5 to 50 grams icodextrin/dextrin per 100 ml of aqueous solution, and (iii) purified water;
- monitoring analyte concentration associated with the infusate introduced into the peritoneal cavity using an analyte sensor;
- and
- receiving an output from the analyte sensor indicative of the analyte concentration.
Dependencies are inferred from the claim text.