Medical instrument
AssigneeTerumo Kabushiki Kaisha
InventorTakashi Okuhara
Life of this patent
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Abstract
The present disclosure can improve durability (particularly, sliding durability) of a surface lubricating layer while maintaining flexibility of a medical instrument. The medical instrument can include: a base whose surface is partially made of a polyester resin; an intermediate layer formed on at least a part of the surface of the base and containing a (meth)acrylic-modified polyester resin and a polyurethane resin; and a surface lubricating layer formed on an upper part of the intermediate layer and containing a block copolymer having a structural unit (A) derived from a hydrophobic monomer and a structural unit (B) derived from a hydrophilic monomer, in which at least one of the hydrophobic monomer and the hydrophilic monomer has a (meth)acryloyl group.
Claims14
A medical instrument comprising:
- a base whose surface is partially made of a polyester resin;
- an intermediate layer formed on at least a part of the surface of the base and containing a (meth)acrylic-modified polyester resin and a polyurethane resin;
- a surface lubricating layer formed on an upper part of the intermediate layer and containing a block copolymer having a structural unit (A) derived from a hydrophobic monomer and a structural unit (B) derived from a hydrophilic monomer;
- wherein at least one of the hydrophobic monomer and the hydrophilic monomer has a (meth)acryloyl group, and wherein the (meth)acrylic-modified polyester resin contains terephthalic acid and isophthalic acid;
- and
- wherein a molar ratio of a structural unit derived from the terephthalic acid to a structural unit derived from the isophthalic acid is 1.5 or more and 4.5 or less.
A catheter comprising:
- a surface that is partially made of a polyester resin;
- an intermediate layer formed on at least a part of the surface and containing a (meth)acrylic-modified polyester resin and a polyurethane resin;
- a surface lubricating layer formed on an upper part of the intermediate layer and containing a block copolymer having a structural unit derived from a hydrophobic monomer and a structural unit derived from a hydrophilic monomer;
- at least one of the hydrophobic monomer and the hydrophilic monomer has a (meth)acryloyl group, and wherein the (meth)acrylic-modified polyester resin contains terephthalic acid and isophthalic acid, and a molar ratio of a structural unit derived from the terephthalic acid to a structural unit derived from the isophthalic acid is 1.5 or more and 4.5 or less;
- and
- wherein the hydrophobic monomer contains at least one selected from the group consisting of glycidyl acrylate, glycidyl methacrylate, 3,4-epoxycyclohexylmethyl acrylate, 3,4-epoxycyclohexylmethyl methacrylate, and β-methylglycidyl methacrylate, and the hydrophilic monomer contains at least one selected from the group consisting of N,N-dimethylacrylamide, N,N-diethylacrylamide, acrylamide, 2-hydroxyethyl acrylate, and 2-hydroxyethyl methacrylate.
A method of coating a medical instrument, the method comprising:
- applying an intermediate layer containing a (meth)acrylic-modified polyester resin and a polyurethane resin on at least a part of a surface of a base, the surface being partially made of a polyester resin, the (meth)acrylic-modified polyester resin containing terephthalic acid and isophthalic acid, and a molar ratio of a structural unit derived from the terephthalic acid to a structural unit derived from the isophthalic acid is 1.5 or more and 4.5 or less;
- and
- applying a surface lubricating layer on an upper part of the intermediate layer, the surface lubricating layer containing a block copolymer having a structural unit derived from a hydrophobic monomer and a structural unit derived from a hydrophilic monomer, and wherein at least one of the hydrophobic monomer and the hydrophilic monomer has a (meth)acryloyl group.
Dependencies are inferred from the claim text.