Method for treating active bleeding using biocompatible hemostatic and sealant compositions

A method of using a combination of a biocompatible modified starch hemostatic product and a biocompatible sealant gel to treat a bleeding wound within or on a mammal, comprising:

• applying a first amount of said biocompatible modified starch hemostatic product to said bleeding wound;
• waiting for a first period of time to permit the biocompatible modified starch hemostatic product to hydrate and adhere to the wound and form a first absorbent layer on the wound surface;
• and,
• applying a second amount of said biocompatible sealant gel to the bleeding wound, after formation of the first absorbent layer, wherein the biocompatible sealant gel comprises a material different from the biocompatible modified starch hemostatic product and is adapted to gelatinize in less than three minutes upon contact with the wound and to form a second sealing layer over the first absorbent layer and wherein said first amount and said second amount in combination are sufficient to cause at least one of:
• hemostasis in said bleeding wound, wound sealing in said wound, reducing exudation of said bleeding wound, promoting tissue healing of said wound, protecting a surface of said wound, and avoiding infection of said wound.