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AssigneesSeoul National University R&Db Foundation, Sungkwang Medical Foundation
InventorsByung-Soo Kim, Han Young Kim, In Bo Han, Hemant Kumar
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Disclosed herein is a nanovesicles from adult stem cells containing iron nanoparticles and its use. The nanovesicle according to the present disclosure provides effects of maximizing the efficacy of treating mesenchymal stem cells by pretreating cells with iron nanoparticles; reconstituting the cells in a nano-sized form to facilitate intravenous injection; and increasing the efficiency of targeting disease areas through magnet induction. In particular, the present disclosure can replace mesenchymal stem cells as a cell therapeutic agent, and it can be applied to various diseases as a novel biopharmaceutical drug because it can increase the function and efficiency of an exosome-based therapeutic agent.
An artificial iron-nanovesicle, which is an artificial iron-nanovesicle prepared from an adult stem cell comprising iron nanoparticles therein, wherein the nanovesicle is administered intravenously to a subject, and after the administration, the nanovesicle is targeted through a step of targeting the administered nanovesicle to an organ or tissue of the subject by applying magnetism to the organ or tissue of the subject,
An artificial iron-nanovesicle comprising the iron nanoparticles prepared by a method, comprising:
Dependencies are inferred from the claim text.