Composition for the protection and repair of the blood brain barrier

A method for the protection of the blood-brain barrier from external attacks selected from an isotopic compound, a toxin and/or a pathogen, comprising

• administering a pharmaceutical composition comprising:
• a biocompatible polymer of the following general formula (I)
• AaXxYyZz (I)
• in which:
• A is glucose,
• X represents an R1COOR2 group, in which R1 is a methyl group —CH2— and R2 is a group R21 R22 in which R21 is an anion and R22 is a cation which is an alkali metal or X is —CH2COO—,
• Y represents —R7SO3R8 in which R7 is a bond and R8 is an alkali metal selected from the group consisting of lithium, sodium, potassium, rubidium and cesium or Y is a —SO3- group,
• Z is phenylalanine or acetate;
• a represents the number of monomers,
• x represents the degree of substitution of monomers A by X groups,
• y represents the degree of substitution of monomers A by Y groups,
• wherein x is between 10 and 150%,
• wherein the degree of substitution “y” is between 10 and 170%, and
• wherein the degree of substitution of all the monomers A by Z groups represented by “z” is between 1 and 50%,
• to an individual at risk from external attacks selected from an isotopic compound, a toxin and/or a pathogen;
• wherein the pharmaceutical composition is administered orally, nasally, subcutaneously, intramuscularly, intravenously, intraarterially, intracranially, or intrathecally.