Transdermal delivery formulation
AssigneeTrs II, LLC
InventorsTed Schwarzrock, Gary Cleary
Life of this patent
Estimating the term…
Abstract
Compositions and methods for delivering vitamin D to a subject. In one embodiment the invention provides a transdermal patch for the transdermal administration of vitamin D comprising: (a) a backing layer that serves as the outer surface of the patch during use; (b) an adhesive drug reservoir layer for affixing the patch to skin; and (c) a release liner, which upon removal exposes the adhesive drug reservoir layer. The adhesive drug reservoir layer can include vitamin D, a polymeric adhesive, an organic solvent, and a permeation enhancer.
Claims17
A transdermal patch for the transdermal administration of cholecalciferol comprising:
- (a) a backing layer that serves as the outer surface of the patch during use;
- (b) an adhesive drug reservoir layer for affixing the patch to skin;
- and
- (c) a release liner, which upon removal exposes the adhesive drug reservoir layer;
- wherein the adhesive drug reservoir layer consists of about 1 to about 10 wt. % cholecalciferol, a polymeric adhesive, about 3-15 wt. % of” before “an organic solvent an organic solvent, and a permeation enhancer;
- and the organic solvent comprises isosorbide dimethyl ether or isopropyl laurate.
A transdermal patch for the transdermal administration of vitamin D3 comprising:
- (a) a backing layer that serves as the outer surface of the patch during use;
- (b) an adhesive drug reservoir layer for affixing the patch to skin;
- and
- (c) a release liner, which upon removal exposes the adhesive drug reservoir layer;
- wherein the adhesive drug reservoir layer consists of 1-10 wt. % cholecalciferol, 60-90 wt. % polymeric adhesive, about 3-15 wt. % of” before “an organic solvent an organic solvent, and 1-15 wt. % transcutol;
- and wherein the organic solvent comprises isosorbide dimethyl ether or isopropyl laurate.
Dependencies are inferred from the claim text.