Methods and systems for treatment of acute ischemic stroke
AssigneeRoute 92 Medical, Inc.
InventorsMichi E. Garrison, Tony M. Chou
Life of this patent
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Abstract
Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.
Claims16
A system for intracranial access through a patient's vasculature to access an intracranial occlusion, the system comprising:
- a distal access catheter comprising a distal end forming a leading edge, the distal access catheter having an inner diameter of 0.070″-0.095″;
- and
- an inner member for advancing the distal access catheter through the patient's vasculature to a terminal portion of an internal carotid artery, the inner member having a proximal section and a distal tip region having a tapered section, wherein an axis of the inner member passes centrally through the proximal section and through the distal tip region, wherein the proximal section, proximal to the distal tip region, has a cylindrical surface having an outer diameter greater than the distal tip region, wherein the proximal section is configured to advance the inner member through the patient's vasculature, and wherein the distal tip region having the tapered section has a size and a flexibility configured to reach the intracranial occlusion, wherein the proximal section and the distal tip region forming a single-lumen passage having a single distal opening configured for passage and relative movement of a wire,
- wherein, in use, the cylindrical surface of the inner member is maintained at least partially distal of the distal end of the distal access catheter during advancement through the patient's vasculature, and
- wherein the outer diameter of the cylindrical surface is sized to substantially correspond to the inner diameter of the distal access catheter to prevent separation between the inner member and the leading edge of the distal access catheter while the distal access catheter is advanced through at least a curved portion of the patient's vasculature, and
- wherein the cylindrical surface has a length to allow axial movements of the inner member relative to the distal access catheter while the distal access catheter is advanced through the curved portion of the patient's vasculature without causing separation of the inner member from the inner diameter of the distal access catheter.
A method of accessing an intracranial occlusion through a patient's vasculature, the method comprising:
- advancing an inner member through the patient's vasculature to reach the intracranial occlusion, the inner member having a proximal section and a distal tip region having a tapered section, the inner member having an axis passing centrally through the proximal section and through the distal tip region, wherein the proximal section, proximal to the distal tip region has a cylindrical surface having an outer diameter greater than a diameter of the distal tip region, wherein the proximal section is configured to advance the inner member through the patient's vasculature, and wherein the distal tip region having the tapered section has a size and a flexibility configured to reach the intracranial occlusion, wherein the proximal section and the distal tip region have a passage therethrough configured for passage and relative movement of a wire, and wherein the inner member is operatively connected to a distal access catheter having an inner diameter of 0.070″-0.095″ and having a distal inner diameter substantially corresponding to the outer diameter of the cylindrical surface and wherein the distal access catheter is movable axially relative to the cylindrical surface;
- maintaining the tapered section of the distal tip region at least partially outside of a distal end of the distal access catheter while the distal access catheter is advanced through at least a curved portion of the patient's vasculature and while causing axial movements of the inner member relative to the distal access catheter, the distal inner diameter of the distal access catheter and the outer diameter of the cylindrical surface being sized and having a length to prevent separation between the inner member and a leading edge of the distal access catheter;
- and
- manipulating the inner member and distal access catheter through the patient's vasculature to a terminal portion of an internal carotid artery using axial movements of the inner member relative to the distal access catheter to advance the distal access catheter through regions of the patient's vasculature having a high tortuosity and without causing separation of the cylindrical surface from the distal inner diameter of the distal access catheter.
Dependencies are inferred from the claim text.