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US 12,622,609 B2Granted
Wearable systems, devices and methods for measurement and analysis of body fluids
AssigneeNix, Inc.
InventorsKenneth Ritsher, Shawn Mishra, Brett Cochran, Daniel Tonderys, Michael Roberts, Meridith Unger Cass
Life of this patent
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Abstract
Systems, devices and methods are described herein for various embodiments of a sample analysis system that is worn by a user, the sample analysis system configured to collect a sample of bodily fluid, and measure and analyze the bodily fluid to determine a property of the bodily fluid and/or a health parameter (e.g., degree of hydration, electrolyte losses, perspiration rate, etc.) of the user.
Claims19
A wearable apparatus, comprising:
- a processor;
- a sample collection region having an inlet and configured to receive, via the inlet, an initial volume of bodily fluid of a user;
- an access port in fluidic communication with the sample collection region;
- a flow channel, in fluid communication with the access port and configured to direct a portion of the initial volume of bodily fluid towards a set of electrodes,
- the set of electrodes including an excitation electrode and a sensing electrode, the excitation electrode configured to apply an excitation signal to the portion of the initial volume of bodily fluid, and the sensing electrode configured to receive a response signal from the portion of the initial volume of bodily fluid in response to the excitation signal, the sensing electrode configured to transmit the response signal to the processor to calculate an impedance associated with the portion of the initial volume of bodily fluid;
- and
- a temperature sensor configured to measure a temperature associated with the portion of the initial volume of bodily fluid, the temperature sensor configured to transmit the measured temperature to the processor, the processor configured to estimate (a) a core body temperature of the user based on the measured temperature, and (b) a rate of loss of hydration of the user based on a correlation between the impedance and a salinity of the bodily fluid.
4 more elements
A system, comprising:
- a memory storing a set of instructions;
- a processor coupled to the memory, and configured to execute the instructions stored in the memory;
- and
- a wearable device including
- a sample collection region configured to receive an initial volume of bodily fluid of a user;
- an access port in fluidic communication with the sample collection region;
- a flow channel, in fluid communication with the access port and configured to direct a portion of the initial volume of bodily fluid towards a set of electrodes;
- the set of electrodes, including an excitation electrode and a sensing electrode, the excitation electrode configured to apply an excitation signal to the portion of the initial volume of bodily fluid, and the sensing electrode configured to receive a response signal from the portion of the initial volume of bodily fluid and in response to the excitation signal;
- and
- a temperature sensor configured to measure a temperature associated with the portion of the initial volume of bodily fluid;
- wherein the instructions, when executed, are configured to cause the processor to:
- send the excitation signal to the excitation electrode;
- receive the response signal from the sensing electrode;
- calculate, based on the response signal, an impedance associated with the portion of the initial volume of bodily fluid;
- receive, from the temperature sensor, a signal associated with the measured temperature, and
- calculate, (a) a core body temperature of the user based on the measured temperature, and (b) a rate of loss of hydration of the user based on a correlation between the impedance and a salinity of the bodily fluid.
13 more elements
Dependencies are inferred from the claim text.