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US 12,618,838 B2Granted
Single domain VHH antibodies against SARS-CoV-2 virus
AssigneeUniversidad Austral De Chile
InventorsAlejandro Rojas, Guillermo Valenzuela, Ronald Jara, Johanna Himelreichs, Constanza Salinas, Teresa Pinto, Natalia López, Yorka Cheuquemilla, Alexei Cuevas, Zaray Miranda, Benjamín Uberti, Ananda Muller
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Abstract
The invention provides a set of novel Single domain VHH antibodies against SARS-CoV-2 (SEQ ID No 1-6) and their use to detect and neutralize the wild type virus.
Claims14
A VHH against the Spike protein of SARS-COV-2, wherein the VHH comprises a set of three CDRs having aminoacidic sequences selected from the group consisting of:
- SEQ ID NOs:
- 7, 8, and 9;
- SEQ ID NOs:
- 10, 11, and 12;
- and SEQ ID NOs:
- 13, 14, and 15.
3 more elements
Dependencies are inferred from the claim text.