System and method for creating tissue

A tissue enclosure for the creation of tissue comprising:

• a core having an open cavity, at least one monitoring area and at least one opening into the cavity, the core accommodating at least one material ingress and at least one material egress, the core containing the tissue, a granular scaffolding supporting the tissue, media, and metabolism products from the tissue;
• an incoming chamber in fluidic communication with said cavity and admitting a first material, the incoming chamber emitting the first material in response to a differential pressure within the tissue enclosure;
• at least one first filtration zone operably positioned between the incoming chamber and the core, the at least one first filtration zone subjecting the first material to at least one filter having a first pore size;
• an effluent chamber in fluidic communication with said cavity;
• and
• at least one second filtration zone operably positioned between effluent chamber and the core, the at least one second filtration zone subjecting the first filtered material, the media, the tissue, and the metabolism products to at least one filter having a second pore size,
• wherein the tissue enters the cavity through the at least one opening, and
• wherein the tissue is confined within the cavity by the at least one first filtration zone and the at least one second filtration zone, and
• wherein the life of the tissue is maintained by the first material entering the cavity through the at least one material ingress and by the metabolism products exiting the cavity through the at least one material egress.