Microfluidic device
AssigneeTechnische UniversitäT Wien
InventorsSarah Spitz, Peter Ertl, Jens Schwamborn, Silvia Bolognin
Life of this patent
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Abstract
The present invention relates to a microfluidic device (1) for cultivating cells, in particular for generating brain organoids, comprising at least two fluid channels (2) positioned essentially opposite to each other and a main chamber (3) located between the fluid channels (2), wherein the main chamber (3) comprises at least one preferably sealable access opening, and each of the at least two fluid channels (2) is fluidly connected to the main chamber (3) at at least one point of contact (4), wherein a slotted structure (5) is provided at each point of contact (4) separating the main chamber (3) from the respective fluid channel (2), wherein the slotted structure (5) is permeable to a liquid.
Claims17
A microfluidic device (1) for cultivating cells, comprising
- at least two fluid channels (2) positioned essentially opposite to each other and a main chamber (3) located between the fluid channels (2), wherein the main chamber (3) comprises at least one access opening, and each of the at least two fluid channels (2) is fluidly connected to the main chamber (3) at at least one point of contact (4),
- wherein a slotted structure (5) is provided at each point of contact (4) separating the main chamber (3) from the respective fluid channel (2), wherein the slotted structure (5) is permeable to a liquid,
- wherein the main chamber (3) comprises an inner top surface (6), an inner bottom surface (7) situated opposite to the inner top surface (6), and an array of pillars (8) extending from the inner top surface (6) into the cross section of the main chamber (3) in direction of the inner bottom surface (7),
- wherein the inner bottom surface (7) of the main chamber (3) comprises at least one recess (9).
Dependencies are inferred from the claim text.