Antiviral immunotherapy by membrane receptor ligation
AssigneeEberhard Karls Universitaet Tuebingen Medizinische Fakultaet
InventorsMichael Schindler, Marius Codrea, Sven Nahnsen, Herwig Koppensteiner, Gundram Jung, Martin Hofmann
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Abstract
The present invention relates to a cytotoxic agent for the prophylaxis and/or treatment of a viral infection which is configured for the selective binding to a membrane receptor of virus-infected T lymphocytes, a pharmaceutical composition containing said cytotoxic agent, the use of the cytotoxic agent for the prophylaxis and/or treatment of viral infections, a method of finding cytotoxic agents, the use of a membrane receptor of virus-infected T lymphocytes which is overexpressed in comparison to non-infected T lymphocytes for the diagnosis of a viral infection.
Claims8
A method for the treatment of HIV infection, comprising the administration to a living being in need in a therapeutically effective amount of a cytotoxic agent, and wherein said cytotoxic agent comprises an agonistic antibody, or a fragment thereof, that selective binds to CD134, and said cytotoxic agent is used alone.
Dependencies are inferred from the claim text.