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US 12,617,814 B2Granted
Neuroactive steroids and methods of use thereof
AssigneeSage Therapeutics, Inc.
InventorsGabriel Martinez Botella, Boyd L. Harrison, Albert Jean Robichaud, Francesco G. Salituro
Life of this patent
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Abstract
3beta, 17beta disubstituted steroidal compounds, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, are provided for the prevention and treatment of a variety of CNS-related conditions.
Claims12
A method for treating a CNS-related condition in a subject, comprising administering to the subject an effective amount of a compound selected from the group consisting of:
- wherein the CNS-related condition is an adjustment disorder, an anxiety disorder, an obsessive-compulsive disorder, a posttraumatic stress disorder, social phobia, a cognitive disorder, a dissociative disorder, an eating disorder, a mood disorder, schizophrenia, a schizoaffective disorder, a sleep disorder, a substance abuse-related disorder, a personality disorder, autism spectrum disorder, a neurodevelopmental disorder, pain, a seizure disorder, stroke, traumatic brain injury, a movement disorder or tinnitus.
Dependencies are inferred from the claim text.