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US 12,617,810 B2Granted
Prodrugs of STAT3 inhibitors
AssigneeTvardi Operating Company, Inc.
InventorsImran Alibhai, Sofia de Achaval, Jeffrey Larson, Brad Henke
Life of this patent
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Abstract
Provided herein, in certain embodiments, are compounds of Formula I: or a pharmaceutically acceptable salt or a solvate thereof, compositions comprising a compounds of Formula I, or a pharmaceutically acceptable salt or a solvate thereof, and uses thereof such as in treating certain diseases or disorders (e.g., cancer, fibrosis, chronic inflammation).
Claims14
A compound of Formula I-B:
- or a pharmaceutically acceptable salt or a solvate thereof, wherein
- A is halo, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl, or C1-4 haloalkoxy;
- RC is hydroxy;
- and
- n is 0 or 1.
2 more elements
Dependencies are inferred from the claim text.