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US 12,617,793 B2Granted
Organic electron transfer mediator and device comprising same
AssigneesI-Sens, Inc., Sogang University Research & Business Development Foundation
InventorsHyunseo Shin, Young Jea Kang, Seok-Won Lee, Bongjin Moon, Myeonghwa Jeong, Sangeun Yoon
Life of this patent
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Abstract
The present invention relates to a novel organic electron-transfer mediator showing an excellent oxidation-reduction potential and a device such as an electrochemical biosensor having improved performance comprising the same.
Claims17
An organic electron-transfer mediator having the structure of Chemical formula 1 below:
- in the formula, R is —H, —F, —Cl, —Br, —I, —NO2, —CN, —CO2H, —SO3H, —NHNH2, —SH, —OH, —NR1R2, an unsubstituted or substituted alkyl group having 1 to 6 carbon atoms, an unsubstituted or substituted alkenyl group having 24 to 6 carbon atoms, or an unsubstituted or substituted aryl group having 6 to 10 carbon atoms, and the R1 and R2 may be each independently H, alkyl having 1 to 3 carbon atoms, or —COOR3, and the R3 may be alkyl having 1 to 6 carbon atoms,
- L (linker) may be one or more selected from the group consisting of a bond, a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted alkenyl group having 2 to 20 carbon atoms, a substituted or unsubstituted ethylene oxide group having 2 to 50 carbon atoms, a substituted or unsubstituted ethylene amine group having 2 to 50 carbon atoms, a substituted or unsubstituted alkoxy group having 1 to 30 carbon atoms, a substituted or unsubstituted aryl or aryloxy group having 6 to 30 carbon atoms, or a substituted or unsubstituted heteroaryl group or heteroaryloxy group having 5 to 30 carbon atoms.
A method for preparation of an organic electron-transfer mediator of Chemical formula 2 below comprising
- i) reacting the compound of Chemical formula 18 below with 1,3-propanesultone to obtain the compound of Chemical formula 19 below;
- and
- ii) reacting the compound of Chemical formula 19 obtained in the i) with alloxan monohydrate and boric acid to obtain the compound of Chemical formula 2 below.
Dependencies are inferred from the claim text.