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US 12,616,703 B2Granted
Methods of contraception using nomegestrol acetate and estradiol
AssigneeTheramex Hq UK Limited
InventorMitra Boolell
Life of this patent
Estimating the term…
Abstract
Provided are methods of contraception using as a first line combined oral contraceptive (COC), a COC composition comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. Said COC compositions are associated with a lower risk of venous thromboembolism (VTE) as compared to other CHCs. The compositions may also be used in methods of treatment in women having conditions linked to menstruation and/or fertility.
Claims19
A method of contraception, comprising:
- (i) identifying a woman desirous of contraception as suitable for receiving a combined hormonal contraceptive (CHC);
- (ii) selecting a CHC, wherein the selected CHC has been identified as a CHC associated with lowest risk of venous thromboembolism (VTE), wherein the selected CHC is a combined oral contraceptive (COC) composition comprising nomegestrol acetate and estradiol or an ester thereof;
- and
- (iii) providing the COC composition comprising nomegestrol acetate and estradiol or an ester thereof to the woman desirous of contraception;
- wherein the woman desirous of contraception is selected from at least one of the following:
- a woman who has been pregnant within the past 3 months, a woman who has or has had cancer, a woman who is having or has had chemotherapy treatment, and a woman who has an increased genetic risk of VTE, and
- wherein the woman desirous of contraception achieves a risk of VTE that is reduced by at least about 10% compared to a reference risk of VTE for a COC containing levonorgestrel.
4 more elements
Dependencies are inferred from the claim text.