Topical lipolysis composition and methods

A composition in the form of a cream or emulsion comprising:

• i) as PHASE A, water, 0.75% sodium lauryl sulfate, 3.0% Azelaic-Kojic Acid mixture (50/50), 3.0% artichoke extract, 3.0% (L)-carnitine-aminophylline mixture (50/50) and 5.0% isopropyl alcohol;
• ii) as PHASE B, 12% stearic acid, 3.0% glyceryl stearate se, 3.0% niacin, 1.0 olive oil, 4.0% dimethicone, 3.5% 2-hydroxyethyl octadecanoate, and 4.0% ethyl alcohol;
• iii) as PHASE C, 5.0% linoleic acid, 0.5% tocopherol acetate, 5.5% lactic acid, 5.0% niacinamide, 0.5% evening primrose oil;
• iv) as PHASE D, 0.5% lecithin, 9.0% sodium deoxycholate, and 0.75% polyoxyethylene lauryl ether and 0.50% phenoxyethanol;
• and
• vi) as PHASE E, 0.5% triethanolamine and 5.0% caffeine, 2.5% bitter orange extract, 1.0% glycyrrhetinic acid, 0.25% Ginkgo biloba, 1.0% Aloe Barbadensis leaf extract, 1.0% L-carnitine and 0.5% Nelumbo nucifera leaf extract, combined in order.

A composition in the form of a cream comprising:

• deoxycholic acid or salt thereof in a concentration ranging from 0.5% to 30% by wt of the composition;
• phosphatidylcholine in an amount in the range of 0.1-5% by wt.;
• one or more micelle-forming compounds selected from sodium lauryl sulfate, polyoxyethylene lauryl ether, 2-hydroxyethyl octadecanoate, olive oil, stearic acid, and evening primrose oil;
• an Azelaic-Kojic acid mixture;
• an (L)-carnitine-aminophylline mixture;
• linoleic acid, tocopherol acetate, niacinamide and triethanolamine, wherein the composition reduces adipose tissue.