Polyurethane gels
AssigneeGrant Industries, Inc.
InventorsMichael J. Isaacman, Anna K. Croom, Ronald V. Lerum, John Gormley
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Abstract
The present invention relates to gel compositions comprising a polyurethane elastomer. The polyurethane elastomer is formed from the reaction of a polyol, a polyisocyanate, and optionally a polyurethane reaction catalyst, optionally in the presence of a topically acceptable carrier fluid. In some embodiments, the gel composition comprises a personal active ingredient or a healthcare active ingredient, which may be incorporated into the gel composition via a pre-load method or a post-load method. Also provided herein are gel pastes and topical formulations comprising the polyurethane elastomers, and methods of making the same.
Claims13
A gel composition comprising a polyurethane elastomer gel containing a reaction product of:
- (A) a polyisocyanate or a mixture of polyisocyanates comprising two or more isocyanate functional groups;
- (B) a polyol or mixture of polyols comprising two or more hydroxyl functional groups;
- (C) polyurethane reaction catalyst;
- and
- (D) topically acceptable carrier fluid acting as a solvent, the topically acceptable carrier fluid being selected from the group consisting of esters, triglycerides, hydrocarbons, oils, and combinations thereof, and the solvent being acceptable for cutaneous surfaces;
- wherein the reaction product has an elastomeric matrix with the topically acceptable carrier fluid entrapped in the elastomeric matrix;
- and
- wherein the composition is silicone-free.
A gel composition comprising a polyurethane elastomer gel containing a reaction product of:
- (A) castor oil, dilinoleic acid/propane diol copolymer, or dilinoleic acid/dilinoleic diol copolymer;
- (B) isophorone diisocyanate, pentamethylene diisocyanate trimer or hexamethylene diisocyanate trimer, wherein a molar ratio of isocyanate groups to hydroxyl groups is about 1:1 to about 1:2;
- (C) polyurethane reaction catalyst;
- and
- (D) topically acceptable carrier fluid acting as a solvent at a concentration of 60% (w/w) to 99.9% (w/w) of the gel composition, the topically acceptable carrier fluid being selected from the group consisting of esters, triglycerides, hydrocarbons, oils, and combinations thereof, and the solvent being acceptable for cutaneous surfaces;
- wherein a personal care or healthcare active ingredient is optionally incorporated into the polyurethane elastomer gel by dissolving the personal care or healthcare active ingredient in the topically acceptable carrier fluid during formation of the polyurethane elastomer gel, or by admixing the personal care or healthcare active ingredient with a formed polyurethane elastomer gel;
- wherein the reaction product has an elastomeric matrix with the topically acceptable carrier fluid entrapped in the elastomeric matrix;
- and
- wherein the composition is silicone-free.
Dependencies are inferred from the claim text.