Three-dimensional thin-film leaflet valve device
AssigneeNininger Medical, Inc.
InventorsDaniel Corey Anderson, Lowie Michel Roger Van Assche, Hussain Soaeb Rangwala, Christopher S. Malaisrie
Life of this patent
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Abstract
Examples of the disclosure are directed toward a valve device comprising an opening and a leaflet and methods of operating and manufacturing the valve device. In some embodiments, the leaflet is a three-dimensional thin-film leaflet, and the leaflet comprises a dome portion. In a first configuration, the leaflet of the valve device may occlude the opening of the device. In a second configuration, the leaflet may not occlude the opening, and blood may flow across the opening of the device. The valve device may be collapsible for transportation in a catheter.
Claims17
A valve device, comprising:
- an opening,
- a leaflet comprising:
- a downstream surface to trap blood pumped by a heart muscle, and
- an upstream surface to selectively occlude the opening when the leaflet's downstream surfaces trap blood pumped by the heart muscle, wherein the upstream surface comprises a dome portion,
- wherein:
- the leaflet is a three-dimensional thin-film leaflet,
- a shape of the leaflet includes a plurality of profiles,
- each profile includes dimensions of an interfacing surface height, an outer cylindrical surface height, and a profile slope angle, and
- the profile slope angle is associated with geometries of the dome portion, and
- a frame defining the opening and comprising anchoring prongs, wherein:
- the leaflet is attached to the frame, and
- when the frame is in a partially deployed configuration, the anchoring prongs are at an angle between 15 and 60 degrees relative to an axis from the downstream surface to the upstream surface.
A method of operating an artificial valve comprising:
- deploying the artificial valve;
- in response to blood pumped by a heart muscle in a direction from a downstream surface to an upstream surface of a thin-film leaflet of the artificial valve:
- selectively occluding an opening of the artificial valve with the upstream surface, wherein the upstream surface comprises a dome portion, and
- trapping the blood pumped by the heart muscle with the downstream surface;
- and
- in response to blood flow in a direction from the upstream surface to the downstream surface:
- deforming, with a force of the blood flow, the leaflet, and
- allowing the blood flow across the opening,
- wherein:
- the leaflet is a three-dimensional thin-film leaflet,
- a shape of the leaflet includes a plurality of profiles,
- each profile includes dimensions of an interfacing surface height, an outer cylindrical surface height, and a profile slope angle, and
- the profile slope angle is associated with geometries of the dome portion, and
- deploying the artificial valve comprises configuring a frame of the artificial valve to a partially deployed configuration, wherein when the frame is in the partially deployed configuration, anchoring prongs of the frame are at an angle between 15 and 60 degrees relative to an axis from the downstream surface to the upstream surface.
A method of manufacturing a valve device comprising:
- fabricating a three-dimensional thin-film leaflet via vacuum deposition, PVD, CVD, or any combination thereof, wherein the thin-film leaflet comprises:
- a downstream surface, and
- an upstream surface, wherein the upstream surface comprises a dome portion, wherein:
- a shape of the leaflet includes a plurality of profiles,
- each profile includes dimensions of an interfacing surface height,
- an outer cylindrical surface height, and a profile slope angle, and
- the profile slope angle is associated with geometries of the dome portion;
- providing a plurality of cells;
- forming a frame by coupling the plurality of cells, wherein the frame defines an opening of the valve device;
- and
- attaching the leaflet to the frame.
Dependencies are inferred from the claim text.